Hades 2 - This almost-immortal sun and moon build is kind of cool

Total Eclipse's Eminence upgrade + a high MP cost omega can grant invulnerability for large portions of combat. Just watch out when charging up for the next round.

Hephaestus' Mint Condition is also a nice pickup to give some safety for the first charge of each room.

0:13 Cerberus
8:43 Chronos