JRF EXPRESS | GENETICS - Unit 08 - Lec - 02 | CSIR NET 2025 | IFAS

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INHERITANCE BIOLOGY

A) Mendelian principles : Dominance, segregation, independent assortment.
B) Concept of gene : Allele, multiple alleles, pseudoallele, complementation tests
C) Extensions of Mendelian principles : Codominance, incomplete dominance, gene interactions, pleiotropy, genomic imprinting, penetrance and expressivity, phenocopy, linkage and crossing over, sex linkage, sex limited and sex influenced characters.
D) Gene mapping methods : Linkage maps, tetrad analysis, mapping with molecular markers, mapping by using somatic cell hybrids, development of mapping population in plants.
E) Extra chromosomal inheritance : Inheritance of Mitochondrial and chloroplast genes, maternal inheritance.
F) Microbial genetics : Methods of genetic transfers – transformation, conjugation, transduction and sex-duction, mapping genes by interrupted mating, fine structure analysis of genes.
G) Human genetics : Pedigree analysis, lod score for linkage testing, karyotypes, genetic disorders.
H) Quantitative genetics : Polygenic inheritance, heritability and its measurements, QTL mapping.
I) Mutation : Types, causes and detection, mutant types – lethal, conditional, biochemical, loss of function, gain of function, germinal verses somatic mutants, insertional mutagenesis.
J) Structural and numerical alterations of chromosomes : Deletion, duplication, inversion, translocation, ploidy and their genetic implications.
K) Recombination : Homologous and non-homologous recombination including transposition.


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