Covid19 Multiple Sequence Alignments and Trees TCoffee by using Biopython in Python

#Biopython #Bioinformatics #TCoffee
Multiple Sequence Alignment (MSA) is generally the alignment of three or more biological sequences (protein or nucleic acid) of similar length. From the output, homology can be inferred and the evolutionary relationships between the sequences studied.
T-Coffee is a multiple sequence alignment software using a progressive approach. It generates a library of pairwise alignments to guide the multiple sequence alignment. It can also combine multiple sequences alignments obtained previously and in the latest versions can use structural information from PDB files.
In this tutorial, I will describe how to perform multiple sequence alignment and phylogenetic trees in python using Biopython and TCoffee software. The raw sequence files are Covid 19 Spike proteins retrieved from NCBI/Genbank database.
For Code refer to my GitHub link below
https://github.com/KhaidirKhaizuki/Bi...